A non-designer colleague asked today if he should use the TrueType or OpenType version of a font he needed to install. For the digital space, there really isn’t much to consider in terms of quality between TrueType (.ttf) and OpenType (.otf), since both allow for hinting (anti-aliasing) for increased on-screen legibility, although I’ll opt for OpenType given the choice as they allow for a much larger character set, e.g. small capitals and ligatures. Fonts.com cover font selection in more detail if you want to read further, and only because it’s short and sweet, here’s what Microsoft has to say on TrueType, OpenType and Postscript fonts.
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